Portable air cleaners can be used in any dry area of your home. The most likely area is the room where it can be of most benefit - where there is the largest concentration of allergens, or the bedroom where you spend several hours of a 24 hr period. You can even take a small unit with you on vacation for use in motel rooms. If you intend to transfer it from room to room often, you may want to consider a compact model. Find a level and secure spot for it close to a plug-in outlet, and at least 3" or so from the wall for adequate air circulation. Certain models require more clearances read the product manual.